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cobicistat will improve the stage or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Carefully. A lessened dose of diazepam may very well be expectedMonitor Carefully (1)crofelemer improves levels of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Crofe